EXPERT STUDY OF TRICYCLIC ANTIDEPRESSANTS
DOI:
https://doi.org/10.32353/khrife.2016.33Keywords:
tricyclic antidepressants, tianeptine, amitriptyline, imipramine, doxepin, clomipramine, qualitative reactions, thin-layer chromatography, IR spectroscopy, absorption bandsAbstract
Consideration is given to the methods of examining the tricyclic antidepressants (tianeptine, amitriptyline, imipramine, doxepin, clomipramine). We selected the most sensitive reagents allowing to differentiate and identify these medicines; carried out their examinations by thin-layer chromatography; selected the organic solvent systems and obtained chromatographic characteristics. The IR spectroscopy method was used to determine the main absorption bands typical for medicinal substances under examination.
